Wastewater monitoring for drug use has been routine in Europe and Australia for at least a decade but is quickly spreading across the United States. Biobot Analytics, a biotechnology company that was one of the CDC’s go-to labs for COVID wastewater tracking, now has federal funding from the National Institute on Drug Abuse and is working with 70 sites across 43 states to monitor wastewater for illicit drugs. Other commercial and academic organizations are pursuing similar initiatives.